Jesus telling us when "the end will come" (Matthew 24) began with the disciples asking, "what will be the sign of Your coming, and of the end of the age?" and ended with him explaining the master will cut the evil slave "in pieces and assign him a place with the hypocrites."
For the lost, “There is no fear of God before their eyes” (Psalm 36:1; Romans 3:18), but for us, “knowing the fear of the Lord, we persuade men” (2 Corinthians 5:11).
When Paul did not want to “build on another man's foundation” and instead “preach the gospel, not where Christ was named” (Romans 15:20) that was because where “he was not announced, they shall see; and those who have not heard shall understand” (Romans 15:21; Isaiah 52:15).
If you look at the context of what Paul is quoting from Isaiah 52, that's a reference to when “The LORD has made bare his holy arm in the eyes of all the nations; and all the ends of the earth shall see the salvation of our God” (52:10). “He shall be exalted and extolled and be very high; just as many were astonished at you, so His visage was marred more than any man” (52:13-14). This is a clear comparison of his second coming to his first. “Just as” he was made low when he came the first time, he will be made “very high” when he comes the second time in judgment.
It is in that context, then, that Isaiah says, “So shall He sprinkle many nations. Kings shall shut their mouths at Him; For what had not been told them they shall see, And what they had not heard they shall consider” (52:15). Paul was motivated to spread the Gospel in uncharted territory so that those “who had not been told” and “had not heard” would hear the gospel from him before they saw it revealed to “all the ends of the earth.”
Do you know the Good News?
Behold, now is the accepted time;
behold, now is the day of salvation.
2 Corinthians 6:2
Do you know others who do not know the Good News?
Awake to righteousness, and do not sin;
for some do not have the knowledge of God.
1 Corinthians 15:34